Aron Goldhirsch Selected Research

Anthracyclines

8/2015	Final 10-year results of the Breast International Group 2-98 phase III trial and the role of Ki67 in predicting benefit of adjuvant docetaxel in patients with oestrogen receptor positive breast cancer.
3/2009	Infusional fluorouracil, epirubicin, and cisplatin followed by weekly paclitaxel plus bevacizumab in locally advanced breast cancer with unfavorable prognostic features.
10/2008	Topoisomerase IIalpha gene status and prediction of pathological complete remission after anthracycline-based neoadjuvant chemotherapy in endocrine non-responsive Her2/neu-positive breast cancer.
5/2008	Pathologic complete remission rate after cisplatin-based primary chemotherapy in breast cancer: correlation with p63 expression.
1/2006	Multicycle dose-intensive chemotherapy for women with high-risk primary breast cancer: results of International Breast Cancer Study Group Trial 15-95.

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Aron Goldhirsch Research Topics

Disease

183	Breast Neoplasms (Breast Cancer) 05/2023 - 09/2002
90	Neoplasms (Cancer) 01/2023 - 03/2003
8	Disease Progression 09/2019 - 06/2004
8	Neoplasm Metastasis (Metastasis) 11/2016 - 09/2002
6	Triple Negative Breast Neoplasms 01/2016 - 09/2008
5	Cardiovascular Diseases (Cardiovascular Disease) 02/2021 - 06/2003
4	Hypertension (High Blood Pressure) 01/2018 - 12/2007
4	Hypercholesterolemia 04/2017 - 12/2005
4	Ductal Carcinoma 09/2015 - 07/2009
3	Arthralgia (Joint Pain) 01/2018 - 02/2007
3	Melanoma (Melanoma, Malignant) 01/2018 - 08/2013
3	Hot Flashes 11/2016 - 01/2007
3	Lobular Carcinoma 09/2015 - 10/2009
3	Cardiotoxicity 12/2010 - 10/2005
3	Bone Fractures (Bone Fracture) 04/2008 - 06/2003
3	Amenorrhea 07/2007 - 03/2006
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 01/2018
2	Carcinoma (Carcinomatosis) 04/2013 - 09/2003
2	Inflammatory Breast Neoplasms 12/2010 - 09/2008
2	Heart Failure 09/2010 - 02/2007
2	Venous Thromboembolism 10/2007 - 10/2005
2	Uterine Hemorrhage (Uterine Bleeding) 02/2007 - 12/2005
2	Thromboembolism 12/2005 - 06/2003
2	Endometrial Neoplasms (Endometrial Cancer) 12/2005 - 12/2004
1	Myocardial Ischemia (Ischemic Heart Diseases) 02/2021
1	Lung Neoplasms (Lung Cancer) 01/2019

Drug/Important Bio-Agent (IBA)

55	Hormones (Hormone)IBA 05/2023 - 06/2004
47	Tamoxifen FDA LinkGeneric 01/2023 - 06/2003
39	Estrogen ReceptorsIBA 01/2020 - 03/2003
32	Letrozole (Femara)FDA LinkGeneric 02/2021 - 12/2005
28	Progesterone Receptors (Progesterone Receptor)IBA 01/2023 - 03/2003
20	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017 - 04/2003
18	Trastuzumab (Herceptin)FDA Link 09/2019 - 10/2005
18	Fluorouracil (Carac)FDA LinkGeneric 11/2016 - 04/2003
13	Estrogens (Estrogen)FDA Link 01/2023 - 06/2004
13	Methotrexate (Mexate)FDA LinkGeneric 11/2016 - 09/2002
12	Aromatase InhibitorsIBA 02/2021 - 12/2005
11	exemestane (Aromasin)FDA Link 01/2023 - 09/2003
11	Cisplatin (Platino)FDA LinkGeneric 08/2015 - 11/2006
11	SteroidsIBA 08/2013 - 10/2004
9	Phenobarbital (Luminal)FDA Link 10/2021 - 04/2012
9	human ERBB2 proteinIBA 10/2016 - 06/2010
8	ErbB Receptors (EGF Receptor)IBA 01/2023 - 11/2006
8	Capecitabine (Xeloda)FDA Link 01/2017 - 04/2002
8	Epirubicin (Ellence)FDA LinkGeneric 08/2015 - 01/2006
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2003
6	Monoclonal AntibodiesIBA 01/2017 - 10/2005
6	Bevacizumab (Avastin)FDA Link 06/2015 - 10/2008
5	Vinorelbine (Navelbine)FDA LinkGeneric 01/2017 - 02/2006
5	AnthracyclinesIBA 08/2015 - 01/2006
5	Progesterone FDA LinkGeneric 08/2015 - 09/2007
5	Cancer VaccinesIBA 02/2014 - 09/2007
5	VaccinesIBA 01/2014 - 09/2007
4	Gonadotropin-Releasing Hormone (GnRH)FDA Link 10/2019 - 12/2003
4	DNA (Deoxyribonucleic Acid)IBA 12/2015 - 06/2010
4	Neoplasm Antigens (Tumor Antigens)IBA 02/2014 - 12/2007
4	AntigensIBA 02/2014 - 10/2009
4	liposomal doxorubicin (Doxil)FDA Link 04/2013 - 12/2010
3	Epidermal Growth Factor (EGF)IBA 01/2023 - 10/2012
3	Triptorelin Pamoate (Trelstar)FDA Link 10/2019 - 04/2010
3	Paclitaxel (Taxol)FDA LinkGeneric 08/2015 - 09/2008
3	1-dodecylpyridoxal (PLD)IBA 04/2013 - 12/2010
3	Fulvestrant (Faslodex)FDA Link 10/2012 - 11/2007
3	Erlotinib Hydrochloride (CP 358,774)FDA Link 06/2012 - 11/2006
3	Tyrosine Kinase InhibitorsIBA 02/2012 - 11/2006
3	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2010 - 01/2008
3	Leucovorin (Folinic Acid)FDA Link 12/2008 - 09/2002
3	Goserelin (Zoladex)FDA Link 03/2008 - 12/2003
2	Immune Checkpoint InhibitorsIBA 01/2018 - 03/2014
2	CholesterolIBA 04/2017 - 06/2003
2	Estrogen Receptor alphaIBA 11/2016 - 12/2015
2	Lapatinib (GW572016)FDA Link 04/2016 - 02/2012
2	Docetaxel (Taxotere)FDA Link 08/2015 - 01/2008
2	LigandsIBA 02/2015 - 03/2006
2	Cell-Free Nucleic AcidsIBA 06/2014 - 06/2004
2	collagen type I trimeric cross-linked peptideIBA 04/2014 - 06/2003
2	AntibodiesIBA 02/2014 - 08/2013
2	Proteins (Proteins, Gene)FDA Link 11/2012 - 04/2003
2	Anastrozole (Arimidex)FDA LinkGeneric 10/2012 - 06/2004
2	Hemoglobins (Hemoglobin)IBA 06/2012 - 01/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2009 - 06/2004
2	taxaneIBA 03/2009 - 01/2008
2	Toremifene (Fareston)FDA Link 02/2006 - 12/2004
1	antineoplaston A10 (A 10)IBA 01/2020
1	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 10/2019
1	sparfosic acid (PALA)IBA 01/2019
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2018
1	NVP-BKM120IBA 01/2018
1	TOR Serine-Threonine KinasesIBA 01/2018

Therapy/Procedure

91	Therapeutics 05/2023 - 01/2003
75	Drug Therapy (Chemotherapy) 01/2023 - 09/2002
23	Adjuvant Chemotherapy 01/2017 - 04/2003
11	Neoadjuvant Therapy 11/2014 - 05/2005
9	Immunotherapy 01/2019 - 09/2007
7	Radiotherapy 01/2018 - 05/2007
5	Mastectomy (Mammectomy) 01/2018 - 02/2009
3	Segmental Mastectomy (Lumpectomy) 10/2016 - 05/2005
3	Mammaplasty (Breast Reconstruction) 10/2015 - 08/2011
3	Catheters 10/2007 - 10/2005
2	Cell- and Tissue-Based Therapy (Cell Therapy) 02/2014 - 08/2013